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CALZEM Capsules (Calcitriol + Calcium carbonate + Zinc)
Desk of Content material
Composition – “calcitriol calcium zinc capsules”
Every smooth gelatin capsule comprises:
Calcium Carbonate, IP……………… 500 mg
(from an natural supply (Oyster shell) equal to elemental Calcium 200 mg)
Calcitriol, BP …………………. 0.25 mcg
Zinc ……………. 7.5 mg
(as Zinc Sulphate Monohydrate, USP)
Dosage Type
Capsule for oral use.
Description
This formulation combines calcitriol, calcium and zinc.
Calcitriol is the energetic from of vitamin D3 (cholecalciferol). It’s produced within the kidney from the vitamin D metabolite, 25-hydroxyvitamin D3 (25(OH)D3). Vitamin D is vital for the absorption of calcium from the abdomen and for the functioning of calcium within the physique.
The recognized websites of motion of calcitriol are the intestines, bone, kidneys and parathyroid gland. In bone, calcitriol together with the parathyroid hormone stimulates resorption of calcium; within the kidneys, calcitriol will increase the tubular reabsorption of calcium.
Calcium performs a important function within the physique. It’s important for the conventional functioning of nerves, cells, muscle and bone. Calcium prevents bone loss and is related to a modest discount in fracture danger. Calcium and vitamin D preparations are used to forestall or to deal with calcium deficiency. A vitamin D-resistant state might exist in uraemic sufferers due to the failure of the kidneys to adequately produce calcitriol.
Zinc is a dietary complement vital for regular progress and tissue restore. Urinary elimination of zinc is elevated in osteoporotic ladies. Zinc depletion is proven to decrease the response of oral calcitriol when administered orally. Supplementary zinc not solely improves calcitriol response but additionally helps to arrest bone loss in older postmenopausal ladies.