After the opening: 36 months; after that: 6 months. Use within 6 months of the opening. Is it safe to take expired laxatives? Is it safe not to take an over-the-counter drug that has expired? If you have a medicine chest on hand, use your best judgment. After the expiration date, a week or ten years may not have any effect on you, but it will certainly be less effective. Do not use after the expiration date is shown.