We’re frequently asked in our comment section about: vitamin b12 and d3 deficiency symptoms.
How Much To Get?
1. Fatigue
If you’re low or deficient in B12, you’ll likely feel fatigued. As such, having inadequate B12 levels can decrease normal red blood cell production, which can impair oxygen delivery Specifically, a deficiency in B12 or folate can cause megaloblastic anemia.
This condition leads to the formation of large, abnormal, and immature red blood cells and impaired DNA synthesis When your body doesn’t have enough healthy red blood cells to carry oxygen to tissues, you’ll likely feel weak and tired.
What To Know About Vitamin B-12 Deficiency
This deficiency can cause a wide range of symptoms that affect a person’s mental and physical health.
As vitamin B-12 deficiency shares many symptoms with other nutritional deficiencies and health conditions, it is possible that people may neither notice it nor get a diagnosis. Being aware of all of the signs can help people identify the deficiency and seek treatment. Below, we look at the symptoms of vitamin B-12 deficiency and their causes.
Abstract
The array of diagnostic workup for pyrexia of unknown origin (PUO) generally revolves in searching for infections, inflammatory/autoimmune, and endocrine etiologies. A differential diagnosis of fever, hemolytic anemia, and thrombocytopenia can have etiologies varying from infections like malaria, dengue, cytomegalovirus, Ebstein barr virus, Parvovirus, infective endocarditis, to autoimmune disorder (systemic lupus erythromatosis), vasculitis, hemolytic uremic syndrome, thrombotic thrombocytopenic purpura (TTP), autoimmune hemolytic anemia/Evan’s syndrome, paroxysmal nocturnal hemoglobinuri (PNH), or drugs. Nutritional deficiencies (especially vitamin B12 deficiency) as a cause of fever, hemolytic anemia, and thrombocytopenia are very rare and therefore rarely thought of.
Severe vitamin B12 deficiency may cause fever and if accompanied by concurrent hyper-homocysteinemia and hypophosphatemia can sometimes lead to severe hemolysis mimicking the above-mentioned conditions. We present a case that highlights vitamin B12 and vitamin D deficiency as an easily treatable cause of PUO, hemolytic anemia, and thrombocytopenia, which should be actively looked for and treated before proceeding with more complicated and expensive investigation or starting empiric treatments. Keywords: Fever, hemolytic anemia, homocysteine, hypophosphatemia, vitamin B12, vitamin D.