In this article we will be discussing a very common question: vitamin c and glutathione.
Abstract
The present study was conducted to assess the status of vitamin C among healthy young adults in relation to serum antioxidant parameters [glutathione (GSH), thiols, and total antioxidant capacity, (TAC)], and oxidative stress markers [malondialdehyde (MDA), and nitrites plus nitrates (NN)]. A prospective study included 200 young adults, and their dietary intake was assessed by using food diaries. Fasting plasma vitamin C, serum levels of GSH, thiols, TAC, MDA, and NN were measured using biochemical assays.
It was observed that 38% of the enrolled subjects, n=76, had an adequate dietary intake of vitamin C (ADI group). Meanwhile, 62%, n=124, had a low dietary intake of vitamin C (LDI group) as compared to the recommended dietary allowances. The fasting plasma level of vitamin C was significantly higher in the ADI group as compared to the LDI group.
In the ADI group, positive correlations were found between plasma vitamin C and serum antioxidant parameters (GSH, thiols, and TAC). Meanwhile, the plasma vitamin C was negatively correlated with serum MDA and NN levels.
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Subjects consumed self-selected vitamin C-restricted diets, and, under double-blind conditions, ingested placebo daily for week 1 (baseline), 500 mg L-ascorbate/d for weeks 2-3, 2000 mg L-ascorbate/d for weeks 4-5, and placebo daily for week 6 (withdraw).
However, the increases in plasma vitamin C and red blood cell glutathione were not correlated (r = 0.22). After the placebo-controlled withdraw period, red blood cell glutathione did not differ from baseline.
1. Consume Sulfur-Rich Foods
It’s required for the structure and activity of important proteins and enzymes in the body.
Sulfur is found in two amino acids in food: methionine and cysteine. However, there are vegetarian sources of sulfur as well, such as cruciferous vegetables like broccoli, Brussels sprouts, cauliflower, kale, watercress and mustard greens. Allium vegetables, including garlic, shallots and onions, also boost glutathione levels — likely due to their sulfur-containing compounds
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These are off label practice and depend on the experience and comfort of the treating physician. The overall support of the same is weak at the moment based on medical literature. Based on your skin type, a dermatologist will recommend you appropriate products.
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Your dermatologist will decide a treatment plan for you after a consultation. Answered
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