This blog post will walk you through: vitamin d and zinc. Don’t worry, we’ve got all the answers about this subject.
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April 5, 2021
By Robert H. Shmerling, MD, Senior Faculty Editor, Harvard Health Publishing.
Disclaimer:
As a service to our readers, Harvard Health Publishing provides access to our library of archived content. Please note the date of last review or update on all articles.
No content on this site, regardless of date, should ever be used as a substitute for direct medical advice from your doctor or other qualified clinician. There is data that implicates malnutrition as a prognostic factor in Covid 19 severity. Obesity is one end of the malnutrition spectrum and obese patients frequently are micronutrient depleted.
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Components of nutritional immunity. The association of clinical symptoms with vitamin D and zinc status was also examined.
Serum concentration of 25(OH)D were not significantly lower in patients with moderate illness (19 ± 12 ng/mL) than patients with asymptomatic or mild illness (29 ± 18 ng/mL), with a trend noted for a lower serum concentration of 25(OH)D in moderate than asymptomatic or mild illness patients (p = 0.054).
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Udy was to investigate the effects of zinc, vitamin D, and their co-supplementation versus placebo on changes in the Beck Depression Inventory II (BDI-II) score, serum cortisol level, and brain-derived neurotrophic factor (BDNF) in obese/overweight patients with depressive symptoms. The intervention period was 12 wk.
Zinc was significantly more effective than vitamin D on decreasing the depression score. Fifteen patients discontinued participation owing to pregnancy (n = 1), severe anemia (n = 1), and unspecified unwillingness to continue (n = 13).