Vitamin E Toxicity

This blog post will walk you through: vitamin e toxicity.

Merck Manual

The greatest risk from vitamin E toxicity is bleeding. Many people take vitamin E supplements to help prevent certain disorders. Vitamin E supplements do not protect against heart and blood vessel disorders.
Vitamin E, like vitamins A, D, and K, is a fat-soluble vitamin, which dissolves in fat and is best absorbed when eaten with some fat. However, high doses of vitamin E may increase the risk of bleeding, particularly for adults who are also taking an anticoagulant (especially warfarin), which makes blood less likely to clot. Treatment of vitamin E toxicity involves stopping vitamin E supplements.

Msd Manual

Arge amounts of vitamin E usually cause no harm but occasionally muscle weakness, fatigue, nausea, and diarrhea occur. The most significant risk is bleeding, mainly with doses > 1000 mg a day. Plasma tocopherol levels vary with total plasma lipid levels.
High-dose vitamin E supplements do not protect against cardiovascular disorders; whether supplements can protect against tardive dyskinesia is controversial. There is no convincing evidence that doses of up to 2000 units/day slow the progression of Alzheimer disease or decrease the risk of prostate cancer; one study suggested an increased risk of prostate cancer with vitamin E supplementation (1 Reference Relatively large amounts of vitamin E usually cause no harm but occasionally muscle weakness, fatigue, nausea, and diarrhea occur. Many adults take relatively large amounts of vitamin E (alpha-tocopherol 400 to 800 mg/day) for months to years without any apparent harm.
Occasionally, muscle weakness, fatigue, nausea, and diarrhea occur. Thus, the upper limit for adults aged ≥ 19 years is 1000 mg for any form of tocopherol.

What Is Vitamin E Toxicity?

Vitamin E is a fat-soluble vitamin that functions as an antioxidant.
It may decrease your risk of heart disease, certain cancers, vision problems, and brain disorders One of its key functions is to keep blood vessels dilated and prevent clots from forming in your blood vessels The Daily Value (DV) for vitamin E is 15 mg per day.
The following foods are rich in vitamin E Summary Vitamin E is a fat-soluble antioxidant vitamin.

Free Radical Biology And Medicine

It has been demonstrated in animal experiments that vitamin E has neither mutagenic, teratogenic nor carcinogenic properties.
Using double-blind studies involving a large number of subjects, it has been demonstrated that large oral doses of up to 3,200 USP-Units/day led to no consistent adverse effects. From a large body of published data, dosage ranges have been deduced which can be characterized as safe for human subjects even where their use extends over a long period of time. It should, however, be noted that oral intake of high levels of vitamin E can exacerbate the blood coagulation defect of vitamin K deficiency caused by malabsorption or anticoagulant therapy.

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