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Why Does Biotin Affect Thyroid Test?

How does biotin affect thyroid test results? Most commonly, biotin use can result in falsely high levels of T4 and T3 and falsely low levels of TSH, leading to either a wrong diagnosis of hyperthyroidism or that the thyroid hormone dose is too high.

Will 30 mcg of biotin affect thyroid tests? Biotin doses in standard multivitamin preparations (~30 mcg) are unlikely to impact lab tests. 3 However, supplements can have up to 650 times the recommended daily intake of biotin.

How much does biotin affect TSH levels? Two hours after ceasing 5 mg biotin, the levels of free T4, total T3, anti-TPO, anti-Tg, and anti-TSHR significantly increased (all P < . 001), while the level of TSH significantly decreased (P = . 005).

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