Why does biotin cause acne? Currently, there is minimal evidence that taking biotin supplements causes acne. The logic behind such claims has more to do with pantothenic acid, or vitamin B5, than with biotin. Pantothenic acid plays a significant role in the function of the epidermal skin barrier, which is the outermost layer of your skin ( 11 ).
Can biotin make acne worse? You may have heard many beauty influencers insist on a link between biotin and breakouts, but new research suggests that there is minimal evidence that supports the claim that taking biotin supplements will worsen acne.