Why does biotin make me break out? Why Might Biotin Make You Break Out? Biotin can lead to breakouts in the way your body absorbs it and other vitamins. It’s not so much that biotin causes acne. It’s that it prevents your body from absorbing other nutrients that normally help counteract the effects of acne.
Does biotin make you break our? Vitamin B5 helps to regulate the skin’s barrier function (including sebum production), so when excessive biotin is introduced, the vitamin B5 cannot be properly metabolized, the environment of your skin barrier is compromised, and you’ll become more prone to breaking out.