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How Does Biotin Interact With Lab Tests?

What lab tests does biotin affect? Most of the published research on biotin interference covers hormone tests, such as parathyroid hormone (PTH), thyroid stimulating hormone (TSH), T4 and T3 tests, as well as tests for troponin. However, because biotin is used in so many immunoassays, scientists say it could interfere with many others.

Does taking biotin affect blood test results? Biotin in blood or other samples taken from patients who are ingesting high levels of biotin in dietary supplements can cause clinically significant incorrect lab test results.

How long before lab tests should I stop taking biotin? It is recommended that patients who have consumed 5–10 mg biotin wait a minimum of 8 hours before having blood collected for laboratory tests (29, 40, 49). Longer washout periods, up to 72 hours, may be required to prevent interference in assays with interference thresholds <30 ng/mL (<122.8 nmol/L) (29).

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How Does Biotin Interact With Lab Tests

Excess biotin in blood interferes with the biotin used in some, but not all, immunoassays and can cause results to be either falsely increased or falsely decreased. These inaccurate test results can cause healthcare practitioners to misdiagnose and mistreat their patients.

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