J. Christopher Gallagher, Vinod Yalamanchili, Lynette M. Smith, The Impact of Vitamin D on Calcium Absorption in Older Ladies, The Journal of Medical Endocrinology & Metabolism, Quantity 97, Situation 10, 1 October 2012, Pages 3550–3556, https://doi.org/10.1210/jc.2012-2020
Summary
The measurement of calcium absorption after vitamin D isn’t nicely studied. On this examine, we measured calcium absorption earlier than and 1 yr after the administration of accelerating doses of vitamin D3.
Topics and Strategies
A paired t check was performed on the placebo group to check the impact of calcium supplementation with out vitamin D3 on the calcium absorption. The impact of vitamin D dose on the 12-month calcium absorption was analyzed by way of a number of linear regression. Baseline values for serum 25OHD, serum 1,25(OH)2D, calcium absorption, weight, whole calcium consumption and tertiles of calcium consumption, and age had been used as covariates. An identical mannequin analyzing the impact of 12-month serum 25OHD degree with 12-month calcium absorption was additionally studied through the use of a number of linear regression evaluation, adjusting for a similar baseline attribute. To enhance mannequin match, the vitamin D dose and dietary calcium consumption was divided by 1000. Mannequin match was assessed with residual plots. P values <0.05 had been thought of to be statistically important. SAS software program was used for knowledge evaluation.
Outcomes
A major covariate on the 12-month calcium absorption worth with serum 25OHD as a predictor was baseline calcium absorption (P < 0.0001). There was no important impact of baseline serum 1,25(OH)2D (P = 0.58), baseline serum 25OHD (P = 0.56), age (P = 0.60), weight (P = 0.85), whole calcium consumption (P = 0.96), or tertiles of calcium consumption. There was no impact of baseline dietary calcium on 12-month absorption. General, 12-month calcium absorption was extra extremely correlated with 12-month serum 25OHD (P = 0.0019) than with the dose of vitamin D (P = 0.033). The adjusted R2 for the regression mannequin was 0.51 (Desk 3).
Dialogue
These outcomes problem the widespread assumption that vitamin D needs to be used to extend calcium absorption; the identical quantity of calcium may very well be absorbed by consuming a small glass of milk (100 ml) or taking a 100-mg elemental calcium pill.
Acknowledgments – “can vitamin d be absorbed without calcium”
Disclosure Abstract: The authors don’t have anything to reveal.
Abbreviations
References
“can vitamin d be absorbed without calcium”