Contents
Introduction
Corneal collagen crosslinking (CXL) is a minimally invasive process used to forestall development of corneal ectasia reminiscent of keratoconus and post-LASIK ectasia.
Background
In 2015, a Cochrane systemic overview analyzing CXL for treating keratoconus revealed that the proof for the usage of CXL within the administration of keratoconus is restricted due the shortage of correctly carried out Randomized Managed Trials.
Primary Ideas
Current research point out that the presence of oxygen is crucial for efficient CXL.[5]
Indications
There at the moment aren’t any definitive standards for development, however parameters to contemplate are change in refraction (together with astigmatism), uncorrected visible acuity, finest corrected visible acuity, and corneal form (topography and tomography). Different illnesses which may be candidates embrace Pellucid Marginal Degeneration, Terrien Marginal Degeneration, and post-refractive surgical procedure (reminiscent of LASIK, PRK, or Radial Keratotomy) ectasia. The first goal of cross-linking is to halt the development of ectasia.
Contraindications
Within the video proven, anesthetic drops are given, then the speculum is positioned and the epithelium is eliminated. Subsequent, drops of riboflavin are administered, adopted by UV publicity.
Variations in Riboflavin
Hypo-osmolar riboflavin is utilized in skinny corneas with a thickness between 400 and 320 µm to thicken the cornea to a minimal of 400 microns.[6]