Magnesium is a voltage-dependent blocker of N-methyl-d-aspartate (NMDA)-coupled channels. Magnesium ions can cause inflammatory pain and neuropathic pain by a variety of mechanisms. Evidence pointing to a positive interactive effect on pain using magnesium with narcotic analgaes and intravenous general anaesthetics, 14–16 local anaesthetic15 and antidepressants. Using magnesium anesthetic anesthetic anesthetic anesthetic anesthetic anesthetic anesthetic anesthetic anesthetic anesthetic anesthetic anesthetic anesthetic anesthetic anesthetic anesthetic anesthetic anesthetic anesthetic anesthetic anesthetic anesthetic anesthetic anesthetic anesthetic anesthetic ane ane ane