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Estrogen reliably reduces the severity of hot flashes and remain the single most effective treatment. Instead of hormonal therapy, women are turning to vitamins, and other over-the-counter products for relief from hot flashes. After 1 week baseline period, the enrolled patients (n = 51) received placebo (identical in appearance to vitamin E softgel) daily for 4 weeks, followed by 1 week wash out and 400 IU vitamin E (softgel cap) daily for the next 4 weeks.
Diary was used to measure hot flashes before and at the end of the study.
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Materials and methods: This was a triple-blind randomized controlled clinical trial. The participants consisted of 93 postmenopausal women in Ahar city-Iran.
One-way ANOVA, repeated measures ANOVA and ANCOVA tests were used for data analysis. Results: There was no statistically significant difference between groups in terms of demographic characteristics, mean number of hot flashes, mean score of anxiety, sexual function index and menopausal symptoms before the intervention (p > 0.05). The first significant effect of curcumin on hot flashes was observed after four weeks (P = 0.027).
Conclusion: The results of this study showed that oral intake of curcumin and vitamin E significantly reduced hot flashes in postmenopausal women but had no significant effect on anxiety, sexual function and menopausal symptom.
Gynecologic And Obstetric Investigation
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What Is A Hot Flash?
We don’t know exactly what causes them, but they may be related to changes in circulation. Some women have a rapid heart rate or chills, too. When they happen while you sleep, they’re called night sweats.
They can wake you up and may make it hard to get enough rest. A hot flush is a hot flash plus redness in your face and neck.