The Edward Mallinckrodt Division of Pediatrics, Washington College College of Drugs,1 and St. Louis Kids’s Hospital,2 St. Louis, Missouri 63110
Summary
Zinc salts had been added to cell-free virus at numerous concentrations and for numerous lengths of time, and the quantity of infectious virus that remained was measured in a plaque assay. The diploma of inactivation was depending on the size of remedy, the sort and pressure of HSV, and the zinc salt used for the remedy. We report right here on an investigation into the in vitro results of varied zinc salts on 10 randomly chosen scientific isolates of HSV.
MATERIALS AND METHODS
RESULTS
DISCUSSION
In conclusion, HSV scientific isolates may be effectively inactivated by remedy with zinc salts in vitro. The extent of inactivation is dependent upon the pressure of HSV, the focus of zinc, the counterion used, and the size of the remedy.