Recombinant Human MMP-9 Protein, CF Abstract
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Provider Free
CF stands for Provider Free (CF). We sometimes add Bovine Serum Albumin (BSA) as a service protein to our recombinant proteins.
Including a service protein enhances protein stability, will increase shelf-life, and permits the recombinant protein to be saved at a extra dilute focus.
The service free model doesn’t include BSA.
On the whole, we advise buying the recombinant protein with BSA to be used in cell or tissue tradition, or as an ELISA customary.
In distinction, the service free protein is beneficial for purposes, wherein the presence of BSA might intervene.
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Background: MMP-9
Matrix metalloproteinases are a household of zinc and calcium dependent endopeptidases with the mixed skill to degrade all of the elements of the extracellular matrix. MMP-9 (gelatinase B) can degrade a broad vary of substrates together with gelatin, collagen varieties IV and V, elastin and proteoglycan core protein. It’s believed to behave synergistically with interstitial collagenase (MMP-1) within the degradation of fibrillar collagens because it degrades their denatured gelatin types. MMP-9 is produced by keratinocytes, monocytes, macrophages and PMN leukocytes. MMP-9 is current most often of inflammatory responses. Structurally, MMP-9 possibly be divided into 5 distinct domains: a pro-domain which is cleaved upon activation, a gelatin-binding area consisting of three contiguous fibronectin sort II items, a catalytic area containing the zinc binding website, a proline-rich linker area, and a carboxyl terminal hemopexin-like area. Along with the human enzyme, the recombinant mouse MMP-9 can be obtainable (Catalog # 909-MM).
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