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Abstract
Vitamins D and K are both fat-soluble vitamins and play a central role in calcium metabolism. Vitamin D promotes the production of vitamin K-dependent proteins, which require vitamin K for carboxylation in order to function properly. Animal and human studies suggest that optimal concentrations of both vitamin D and vitamin K are beneficial for bone and cardiovascular health as supported by genetic, molecular, cellular, and human studies.
Few intervention trials studied vitamin D and K supplementation with cardiovascular-related outcomes. These limited studies indicate that joint supplementation might be beneficial for cardiovascular health. Current evidence supports the notion that joint supplementation of vitamins D and K might be more effective than the consumption of either alone for bone and cardiovascular health.
As more is discovered about the powerful combination of vitamins D and K, it gives a renewed reason to eat a healthy diet including a variety of foods such as vegetables and fermented dairy for bone and cardiovascular health.
Associated Data
This paper dived into the immunoregulatory effects of supplementing Vitamin D 3 by elaborating a causal loop diagram. Together with D 3 , vitamin K 2 and magnesium should be supplemented to prevent long-term health risks.
Keywords: Vitamin D, COVID-19, Coronavirus, Mortality rate, Immunology
Methodology One of the basic principles that is used to combine valuable scientific findings and knowledge from often interdisciplinary domains is called systems analysis. Causal loop diagrams (CLDs) functioned as a tool to illustrate the principle of causality of 25(OH)D serum levels on the human metabolism and form the basis for systems analysis (Mabin et al., 2006). Cause and effect mechanisms).
Based on these findings, the CLDs have been created and digitized using the Vensim software (Ventana Systems, 2015). Conclusions Recent COVID-19-related data evaluation showed indications that a high 25(OH)D blood serum level might have an impact on the mortality rate of coronavirus patients. Even though ethical issues might arise (Muthuswamy, 2013), the paper’s hypothesis requires clinical randomized trials to verify the circumstantial evidence.
Ethics approval and consent to participate Not applicable. Consent of publication Not applicable.
What Are Vitamins D And K?
Vitamin D and vitamin K are essential, fat-soluble nutrients.
One of vitamin D’s primary functions is to promote calcium absorption and maintain adequate calcium levels in your blood. It’s necessary for blood clotting and promotes the accumulation of calcium in your bones and teeth.
D+K2 – Putting Calcium In Balance
Vitamin D3 and vitamin K2 ensure that calcium is absorbed easily and reaches the bone mass, while preventing arterial calcification.
Helping to keep your heart and bones healthy. Separately, K2 regulates normal blood clotting, whilst D3 supports a healthy immune system and supports muscle functio.