Contents
Introduction
Corneal collagen crosslinking (CXL) is a minimally invasive process used to stop development of corneal ectasia resembling keratoconus and post-LASIK ectasia.
Background
In 2015, a Cochrane systemic evaluate analyzing CXL for treating keratoconus revealed that the proof for using CXL within the administration of keratoconus is proscribed due the dearth of correctly performed Randomized Managed Trials.
Fundamental Ideas
Latest research point out that the presence of oxygen is important for efficient CXL.[5]
Indications
There at present aren’t any definitive standards for development, however parameters to think about are change in refraction (together with astigmatism), uncorrected visible acuity, greatest corrected visible acuity, and corneal form (topography and tomography). Different illnesses that could be candidates embody Pellucid Marginal Degeneration, Terrien Marginal Degeneration, and post-refractive surgical procedure (resembling LASIK, PRK, or Radial Keratotomy) ectasia. The first function of cross-linking is to halt the development of ectasia.
Contraindications
Within the video proven, anesthetic drops are given, then the speculum is positioned and the epithelium is eliminated. Subsequent, drops of riboflavin are administered, adopted by UV publicity.
Variations in Riboflavin
Hypo-osmolar riboflavin is utilized in skinny corneas with a thickness between 400 and 320 µm to thicken the cornea to a minimal of 400 microns.[6]