Why biotin makes you break out? Why Might Biotin Make You Break Out? Biotin can lead to breakouts in the way your body absorbs it and other vitamins. It’s not so much that biotin causes acne. It’s that it prevents your body from absorbing other nutrients that normally help counteract the effects of acne.
Does biotin trigger acne? There is some evidence that biotin may help improve comedonal acne, which is acne that causes blackheads and whiteheads. It may also help control the flaking and irritation that occurs when you take retinoids for acne.