This article aims to clear any doubts and questions you may have about this subject and we will do our best to do so.
How Much To Get?
The answer depends on things including your age, your eating habits and medical conditions, and what medications you take.
Abstract
The array of diagnostic workup for pyrexia of unknown origin (PUO) generally revolves in searching for infections, inflammatory/autoimmune, and endocrine etiologies. We present a case that highlights vitamin B12 and vitamin D deficiency as an easily treatable cause of PUO, hemolytic anemia, and thrombocytopenia, which should be actively looked for and treated before proceeding with more complicated and expensive investigation or starting empiric treatments.
Keywords: Fever, hemolytic anemia, homocysteine, hypophosphatemia, vitamin B12, vitamin D.
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Subjects/methods: We assessed nutritional status in 50 consecutive out patients with disseminated SI-NET, 25 patients in each cohort. The first cohort was descriptive and the second cohort supplemented with vitamin D, B12 and calcium.
Vitamin D deficiency was defined as <50 nmol/l. In patients without prior substitution, 32% had subnormal vitamin B12 levels. Seventy-six percent had low bone density.
In the second cohort with vitamin and mineral supplementation, none had severe vitamin D deficiency, but 28% had moderate deficiency. No patient had subnormal vitamin B12 levels. Sixty percent had low bone density.
The serum levels of vitamin D and B12 were higher and parathyroid hormone (PTH) lower in the second cohort compared with the first cohort (P⩽0,022).
1. Fatigue
Your body’s cells need B12 to function properly. Specifically, a deficiency in B12 or folate can cause megaloblastic anemia.