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Vitamin B12 Toxicity

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Benefits Of Supplementing With Vitamin B12

This nutrient is responsible for numerous functions in your body, including red blood cell formation, energy production, DNA formation and nerve maintenance Though B12 is found in many foods, such as meat, poultry, seafood, eggs, dairy products and fortified cereals, many people don’t get enough of this important vitamin. While people who consume adequate amounts of B12-rich foods and are able to properly absorb and utilize this nutrient don’t necessarily need to supplement, taking extra B12 has been linked to some health benefits.
Although B12 supplements are commonly taken to boost energy levels, there is currently no evidence suggesting that more B12 increases energy in people with adequate levels of this vitamin. However, B12 supplements will most likely increase energy levels in those who are deficient, as this nutrient plays an important role in converting food into energy.

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What Are The Side Effects Of Vitamin B-12?

Oral vitamin B-12 is safe to take at recommended doses for healthy people.
Injectable vitamin B-12, which is used to treat significant deficiencies, can cause the following side effects: mild diarrhea


skin rash





pulmonary edema and congestive heart failure early in treatment

vein thrombosis

sensation of swelling

polycythemia vera (rare, slow growing blood cancer) Vitamin B-12 can cause very rare but serious allergic reactions (anaphylaxis). This includes swelling of the face, tongue, and throat, and difficulty swallowing and breathing. You may need vitamin B-12 supplements if you take any of the following: colchicine


proton pump inhibitors

vitamin C


H2 blockers

aminosalicylic acid Folic acid supplements may interfere with vitamin B-12.
Be sure to tell your doctor if you take folic acid. You may need to take vitamin B-12 separately from the above drugs and supplements — say, one in the morning and one at night — so you can get the full dose of vitamin B-12.

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When Should You See A Doctor?

Seek medical attention if your symptoms get worse or are severe.
Foods with vitamin B-12 include: eggs






Red Meat

How Are Vitamin B-12 Side Effects Treated?

See your doctor if you have bothersome side effects that don’t go away once you stop taking the supplements. Avoid taking supplements if possible, and try to get B-12 from food sources.

Save Citation To File

After a total dose of 12 mg, she developed acne, palpitations, anxiety, akathisia, facial ruddiness, headache, and insomnia.
She improved two weeks after stopping the drug. There were no sequelae nor complications.Discussion: Although these symptoms of cobalamin toxicity were unexpected and unusual, the case reminds us that the administration of any drug is not entirely saf.

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