Vitamin B12 Under Tongue

This article aims to clear any doubts and questions you may have about this subject and we will do our best to do so.

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In fact, one clinical study comparing the same amount of B-12 given orally or under the tongue found they were equally effective at correcting B-12 deficiency over a two-month period.Be aware that sublingual B-12 supplements often contain sugar substitutes such as sorbitol, mannitol or sucralose, which can cause gastrointestinal symptoms in some people.It should also be noted that unlike the vitamin B-12 in foods, the purified form of B-12 found in supplements, including regular and sublingual tablets, does not require stomach acid for it to be made available for absorption. This benefits people with low stomach acid (including many people over the age of 50) or those who take acid blockers such as Pepcid or Zantac, or proton pump inhibitors such as Prevacid, or Prilosec, who are at an increased risk for B-12 deficiency . For those who have difficulty with large pills, keep in mind that only a very small amount of B-12 is required to meet the recommended daily intake and can be obtained in small tablets, including those tested by in its B Vitamins Supplements Review , which includes our Top Pick for vitamin B-12 and the latest information about B-12 dosage and safety and when to take vitamin B-.

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Vitamin B-12

Vitamin B-12 is one of eight compounds that are collectively referred to as B-complex vitamins. B-12 from food and oral supplements is absorbed in the intestines with the help of intrinsic factor, a compound secreted in the stomach.

Sublingual Supplements

Sublingual supplements — either as tablets or liquid drops — are meant to be put under your tongue and absorbed through the mucosal membrane that lines your mouth.

The main advantage of taking sublingual B-12 is supposed to be enhanced absorbability — at least greater than 2 percent — and many companies selling the supplements claim this. However, multiple studies have not supported this contention.


Materials and results Thirty subjects with low serum concentrations of cobalamin participated in the study.
Serum cobalamin concentrations before treatment were 94 ± 30 pmol l−1, 108 ± 17 pmol l−1 and 98 ± 14 pmol l−1 in the sublingual B12, oral B12 and oral B-complex groups, respectively.

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