Vitamin B6 Labcorp

Truth is we’ve been delaying this article for a while until we had enough information & facts to allow us to enlighten our readers. Hopefully by the end of this article you’ll have no doubts about this subject.

Specimen Requirements

A family of water-soluble flavin vitamins that are critical for metabolism and energy generations in the aerobic cell, through oxidative phosphorylation.1-4 These compounds are synthesized in plants and microorganisms and occur naturally in three forms: the physiologically inactive riboflavin, and the physiologically active coenzymes flavin mononucleotide (FMN) and flavin adenine dinucleotide (FAD). Flavin derivatives ingested with the diet (FAD, FMN) are dissociated by gastric acid from their protein binding, transformed by phosphatases to riboflavin, and absorbed in the small intestines.1,2 The reconversion of riboflavin to the coenzymes FMN and FAD occurs in the cytoplasm in many different tissues. Vitamin B2 deficiency leads to reduced activity of the flavin-containing enzymes (glutathione reductase and glutathione peroxidase) which, in turn, allows these peroxidase to express their deleterious effects.

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These may involve the metabolism of various neurotransmitters and amino acids. Inadequate PLP may occur due to genetic, nutritional deficiencies as well as reaction with various drugs. Inherited disorders that affect the CSF PLP level include pyriodx(am)ine phosphate oxidase (PNPO) deficiency, alpha amnioadipic semialdehyde dehydrogenase deficiency, hyperprolinermia type 2 and hypophoshatasia due to alkaline phosphatase deficienc.


Vitamin B6, also known as pyridoxine, is a water-soluble vitamin that helps brain function, the body convert protein to energy and helps the immune system produce antibodies. The body uses it to help break down proteins. The more protein you eat, the more vitamin B6 you need.
High levels of vitamin B6 can cause neurological disorders and numbness. The deficiency of vitamin B6 can cause mouth and tongue sores, irritability, confusion, and depression. Major sources of vitamin B6 include:

Cereal grains and flour

Vegetables like peas, spinach, and carrots

Seeds and nuts

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Milk and cheeses

Fish, meat and eggs


Deficiency of vitamin B6 has been implicated in a wide variety of clinical conditions.
Important in neonatology, it is the syndrome of jittery characteristics, irritability, easy startling, colic, and seizures due to B6 deficiency following ingestion of formula rendered B6 depleted by excessive heating. Vitamin B6 deficiency can be more prevalent in people who:.

Ordering Recommendation

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Arup Laboratories assumes no responsibility for billing errors due to reliance on the CPT codes publishe.

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