Vitamin C 400 Iu

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Antioxidant HEALTH

Vitamin C’s important role in immune health does not stop at the surface.
** During the initial stages of the immune response, white blood cells of the innate immune system start the inflammatory response as one means of dealing with unwelcomed visitors. In a state of inflammation, an abundance of free radicals can be produced. Free radicals cannot differentiate between your own healthy cells and the target of your immune system so they can end up damaging your own cells.
Vitamin C is a powerful antioxidant that helps to fight free radicals. ** It also helps to regenerate other antioxidants like vitamin E to their active state to maintain antioxidant support. **

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In addition to supporting skin integrity and antioxidant health, vitamin C is essential for the optimal functioning of white blood cells.
** During an immune response, white blood cells go through a process of rapid division and multiplication. Vitamin C supports the production of the important B and T cells of the adaptive immune response. ** It also helps special types of cells of the innate immune system called phagocytes do their job, engulfing unwanted compounds.

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Tant in mutagenic, carcinogenic, and aging processes. Although it is plausible that antioxidant vitamins may reduce oxidative DNA damage, evidence from human studies has been sparse and inconsistent. We determined the short-term effects of vitamin C (500 mg/day) and vitamin E (400 IU d-alpha-tocopheryl acetate/day) supplements on oxidative DNA damage in a double-masked, placebo-controlled, 2×2 factorial trial in 184 nonsmoking adults.
Mean duration of supplementation was 2 months. Oxidative DNA damage was measured by 24-h urinary excretion of 8-hydroxy-2′-deoxyguanosine (8-OHdG). The benefits of fruit and vegetable intake became evident with the consumption being at least three servings/day.
In overall and subgroup analyses, there was no significant main effect or interaction effect of the supplements on urinary 8-OHdG. In conclusion, supplementation of diet with vitamin C (500 mg/day) and vitamin E (400 IU d-alpha-tocopheryl acetate/day) had no significant main effect or interaction effect on oxidative DNA damage as measured by urinary 8-OHdG in nonsmoking adults. However, several aspects of a healthy lifestyle were associated with lower oxidative DNA damag.

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