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Vitamin C Wound Healing

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In the inflammatory phase it is required for neutrophil apoptosis and clearance. After wounding, plasma and tissue levels of AA diminish and, as a consequence, supplements may be useful for healing, although levels beyond saturation are excreted Clinicians need to be aware of both the nutritional status of patients with either acute or chronic wounds and the possibility of any AA deficiency which may hinder healin.

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Ence that wound healing in subjects judged not deficient in vitamin C can be significantly accelerated with supplements of this nutrient above the recommended daily allowance (RDA).
Genetic impairment of collagen synthesis has also been observed to be responsive to ascorbic acid supplementation in an 8-year-old boy with Type VI Ehlers-Danlos syndrome.

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International Journal Of Surgery Open

A subclinical deficiency will not often cause the display of the hallmark symptoms of scurvy, but this may lead to an altered collagen synthesis and have major implications for adequate wound healing, such as in the surgical fiel.

Oral Surgery, Oral Medicine, Oral Pathology

Four grams of ascorbic acid daily produced a significant improvement in the quality of newly synthesized collagen but did not alter that formed prior to the supplementation of C. The combined evidence in this review provides a substantial base for further research, both clinical and experimental trials, concerning the interrelationships between vitamin C and the body’s healing potentia.

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