It’s quite a sensitive & complex subject, as such we will do our best at providing a clear and concise article to clear any doubts you may have.
Oxicity is rare but can result from taking high doses of vitamin B6 supplements. Good sources of vitamin B6 include dried yeast, liver, other organ meats, whole-grain cereals, fish, and legumes. Vitamin B6 in very high doses may be prescribed for such disorders as carpal tunnel syndrome or premenstrual syndrome, although there is little evidence of benefit.
Taking very high doses of vitamin B6 may damage the nerves (called neuropathy Polyneuropathy Polyneuropathy is the simultaneous malfunction of many peripheral nerves throughout the body.
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Ed levels of Vitamin B6 are well known. Twenty-six patients were found to have elevated serum B6 levels.
Twenty-one patients (80.8%) reported only sensory complaints. Eight patients had an abnormal quantitative sensory study.
What Does It Mean If Your Vitamin B6 Result Is Too Low?
Many of these are related to amino acid synthesis, fatty acid metabolism and hemoglobin synthesis.
Vitamin B6 also is critical for the release of glucose from glycogen stores; this is why fatigue is one of the symptoms of a deficiency.
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This is because your supplement provided an amount of B6 close to the upper limit (and much more than normally needed) and there is an allowable manufacturing overage, as noted above. However, side effects have generally been reported with daily intakes above 200 mg and, more typically, above 1,000 mg, so, although possible, it would be unusual for the B6 in your supplement alone (if properly made) to cause the side effects you reported.
Foods also contribute B6, but non-fortified foods would be unlikely to put you over the UL since foods naturally rich in B6 (like liver, other meats, potatoes, and bananas) provide about only about 0.25 to 1 mg of B6 per serving.