Division of Nephrology, Sher-I-Kashmir Institute of Medical Sceinces, Soura, Srinagar, India
Summary
Introduction
Vitamin D toxicity is a identified reason behind hypercalcemia and renal failure. The every day requirement of vitamin D is about 200–600 IU and the pores and skin can solely produce round 10,000 IU of vitamin D after complete physique publicity to UV gentle.1 Though vitamin D has a large therapeutic index, its toxicity is well-known and instances of unintentional ingestion, self remedy, and malpractice have been reported. We report right here a case of malpractice-related vitamin D intoxication in an aged male who offered with hypercalcemia, acute renal failure, and psychological obtundation.
Case Report
The PTH degree was 15 ng/L (10–60 ng/L) and the 25-hydroxy vitamin D degree was 302 nM (47–144 nM). The PSA was regular and the myeloma profile was detrimental. The serum calcium and renal features stay regular on observe up.
Dialogue
Our affected person had obtained a slow-release preparation of vitamin D after each 15 days for the final two years, resulting in a cumulative dose of two,10,00,000 IU. This emphasizes the necessity to commonly assess the degrees of vitamin D in sufferers suspected of its deficiency and who’re placed on vitamin D alternative remedy.
Footnotes – “does vitamin d affect kidneys”
References
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“does vitamin d affect kidneys”