What would cause a biotin deficiency? Consuming raw eggs on a regular basis for an extended time causes biotin deficiency because avidin present in egg white tightly binds biotin thus making biotin unavailable for intestinal absorption. Cooking eggs denatures avidin, thus impairing its ability to tightly bind biotin.
How is biotin deficiency treated? Biotinidase deficiency is treated with oral biotin (vitamin H; coenzyme R, part of vitamin B complex) supplements. Treatment should begin as soon as the diagnosis is made. With biotin treatment, symptoms of the disorder may disappear.