Vitamins 696x496 1

Vitamin B6 Levodopa

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As to investigate the role of L-DOPA/carbidopa (CD) therapy on vitamin B6 levels in patients with Parkinson disease (PD). Methods: This is a cross-sectional retrospective study of vitamin B6 plasma levels in 24 patients with PD treated with L-DOPA/CD for 3 or more years, orally or intraduodenally. Patients with low vitamin B6 had been treated with larger doses of L-DOPA/CD, although the differences did not have statistical significance.
Conclusions: Vitamin B6 could play an important role in PD and its levels seem to be influenced by L-DOPA/CD.

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However, this has only been described for patients who used the product in the form of an intestinal gel. Case description: We are describing 3 patients who developed vitamin B6 deficiency while using levodopa/carbidopa in tablet form.
All 3 patients developed symptoms consistent with peripheral axonal polyneuropathy.

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Interactions Between Your Drugs

Plies to: levodopa and Vitamin B6 (pyridoxine)

Ask your doctor before using levodopa together with pyridoxine. You should be advised against taking pyridoxine-containing vitamin supplements.
Do not stop using any medications without first talking to your doctor.

Medical Warning:

It may be necessary to discontinue your pyridoxine, or to add another medicine, carbidopa or benserazide, to lessen the effects of this interaction.Your healthcare professionals (e.g. Do not start, stop, or change the dosage of any medicine before checking with them first.
These medicines may cause some risk when taken together. This information is generalized and not intended as specific medical advice. Consult your healthcare professional before taking or discontinuing any drug or commencing any course of treatment.
Selected from data included with permission and copyrighted by First Databank, Inc. This copyrighted material has been downloaded from a licensed data provider and is not for distribution, except as may be authorized by the applicable terms of use. Conditions OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals.
The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else.

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